Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma

This analysis was performed to assess whether antiepileptic drugs (AEDs) modulate the effectiveness of temozolomide radiochemotherapy in patients with newly diagnosed glioblastoma. The European Organization for Research and Treatment of Cancer (EORTC) 26981-22981/National Cancer Institute of Canada...

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Veröffentlicht in:	Neurology 2011-09, Vol.77 (12), p.1156-1164
Hauptverfasser:	WELLER, M, GORLIA, T, ROSSETTI, A. O, LACOMBE, D, MIRIMANOFF, R.-O, VECHT, C. J, STUPP, R, CAIRNCROSS, J. G, VAN DEN BENT, M. J, MASON, W, BELANGER, K, BRANDES, A. A, BOGDAHN, U, MACDONALD, D. R, FORSYTH, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antineoplastic Agents, Alkylating - therapeutic use Biological and medical sciences Brain Neoplasms - drug therapy Brain Neoplasms - mortality Canada - epidemiology Dacarbazine - analogs & derivatives Dacarbazine - therapeutic use Europe - epidemiology Female Glioblastoma - drug therapy Glioblastoma - mortality Humans Male Medical sciences Middle Aged Neurology Neurosurgery Retrospective Studies Skull, brain, vascular surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Survival Rate - trends Valproic Acid - therapeutic use Young Adult
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