Enhanced Gaussia Luciferase Blood Assay for Monitoring of in Vivo Biological Processes

Secreted Gaussia luciferase (Gluc) has been shown to be a useful tool for ex vivo monitoring of in vivo biological processes. The Gluc level in the blood was used to detect tumor growth, metastasis and response to therapy, gene transfer, and circulating cells viability, as well as transcription fact...

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Veröffentlicht in:	Analytical chemistry (Washington) 2012-01, Vol.84 (2), p.1189-1192
Hauptverfasser:	Bovenberg, M. Sarah S, Degeling, M. Hannah, Tannous, Bakhos A
Format:	Artikel
Sprache:	eng
Schlagworte:	absorption Analytical chemistry Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals antibodies Applied cell therapy and gene therapy Biological and medical sciences Bioluminescence Biotechnology Blood blue light Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes cell viability Chemistry Copepoda - enzymology Exact sciences and technology Fundamental and applied biological sciences. Psychology Gene therapy gene transfer Genes, Reporter Glioma - enzymology Glioma - genetics Glioma - pathology Health. Pharmaceutical industry hemoglobin Humans image analysis Imidazoles - chemistry Imidazoles - metabolism Immunoglobulins Industrial applications and implications. Economical aspects luciferase Luciferases - blood Luciferases - genetics Luminescent Measurements Medical sciences Metastasis Mice Mice, Nude Molecular and cellular biology monitoring Pyrazines - chemistry Pyrazines - metabolism therapeutics transcription factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy Tumor Cells, Cultured Tumors
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