Genome-wide homozygosity and multiple sclerosis in Orkney and Shetland Islanders

There is strong evidence for both genetic and environmental risk factors comprising the aetiology of multiple sclerosis (MS). While much progress has been made in recent years in identifying common genetic variants using genome-wide association studies, alternative approaches have remained relativel...

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Veröffentlicht in:	European journal of human genetics : EJHG 2012-02, Vol.20 (2), p.198-202
Hauptverfasser:	McWhirter, Rebekah E, McQuillan, Ruth, Visser, Elizabeth, Counsell, Carl, Wilson, James F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Age of Onset Aged Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedicine Child Consanguinity Cytogenetics Disease Etiology Female Fundamental and applied biological sciences. Psychology Gene Expression General aspects. Genetic counseling Genes Genetic Predisposition to Disease Genetic variance Genetics Genetics of eukaryotes. Biological and molecular evolution Genome-Wide Association Study Genomes Genotyping Health sciences homozygosity Homozygote Human Genetics Humans Inbreeding Male Medical genetics Medical sciences Middle Aged Molecular and cellular biology Multiple sclerosis Multiple Sclerosis - epidemiology Multiple Sclerosis - genetics Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Pedigree Population Regression analysis Risk Factors Sclerosis Scotland - epidemiology Scotland - ethnology Sex Studies Young Adult
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