Calculating the expected frequencies of potential secondary structure in nucleic acids as a function of stem length, loop size, base composition and nearest-neighbor frequencies

A formula is derived to estimate the expected frequency of potential secondary structure of a given stem length and loop size in a random sequence of nucleotides of known length and composition. An example is provided using the SV40 sequence which shows significant non-randomness in stem length but...

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Veröffentlicht in:	Nucleic acids research 1983-07, Vol.11 (13), p.4655-4663
1. Verfasser:	Fitch, W.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Composition Base Sequence DNA DNA conformation DNA, Viral - genetics equations estimation Mathematics Methods Nucleic Acid Conformation nucleotide sequences simian polyomavirus Simian virus 40 - genetics sv40
Online-Zugang:	Volltext
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