New Therapeutic Approaches to Spinal Muscular Atrophy

Bench to bedside progress has been widely anticipated for a growing number of neurodegenerative disorders. Of these, spinal muscular atrophy (SMA) is perhaps the best poised to capitalize on advances in targeted therapeutics development over the next few years. Several laboratories have achieved com...

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Veröffentlicht in:	Current neurology and neuroscience reports 2012-02, Vol.12 (1), p.42-53
Hauptverfasser:	Lewelt, Aga, Newcomb, Tara M., Swoboda, Kathryn J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Animals Atrophy Cells, Cultured Clinical Trials as Topic Congenital diseases Disease Models, Animal Epidemiology Fractures Genotype Humans Laboratories Medicine Medicine & Public Health Muscular Atrophy, Spinal - genetics Muscular Atrophy, Spinal - pathology Muscular Atrophy, Spinal - physiopathology Muscular Atrophy, Spinal - therapy Nerve and Muscle (M Hirano and LH Weimer Neurology Neurosciences Phenotype Respiratory failure Scoliosis Section Editors Spinal cord Survival of Motor Neuron 1 Protein - genetics Survival of Motor Neuron 1 Protein - metabolism Survival of Motor Neuron 2 Protein - genetics Survival of Motor Neuron 2 Protein - metabolism
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