KIF1Bβ Functions as a Haploinsufficient Tumor Suppressor Gene Mapped to Chromosome 1p36.2 by Inducing Apoptotic Cell Death

Deletion of the distal region of chromosome 1 frequently occurs in a variety of human cancers, including aggressive neuroblastoma. Previously, we have identified a 500-kb homozygously deleted region at chromosome 1p36.2 harboring at least six genes in a neuroblastoma-derived cell line NB1/C201. Amon...

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Veröffentlicht in:The Journal of biological chemistry 2008-09, Vol.283 (36), p.24426-24434
Hauptverfasser: Munirajan, Arasambattu K., Ando, Kiyohiro, Mukai, Akira, Takahashi, Masato, Suenaga, Yusuke, Ohira, Miki, Koda, Tadayuki, Hirota, Toru, Ozaki, Toshinori, Nakagawara, Akira
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Sprache:eng
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