Three Consecutive Arginines Are Important for the Mycobacterial Peptide Deformylase Enzyme Activity

Genes encoding the peptide deformylase enzyme (def) are present in all eubacteria and are involved in the deformylation of the N-formyl group of newly synthesized polypeptides during protein synthesis. We compared the amino acid sequences of this enzyme in different mycobacterial species and found t...

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