RDR6-mediated synthesis of complementary RNA is terminated by miRNA stably bound to template RNA

RNA-dependent RNA polymerase RDR6 is involved in the biogenesis of plant trans-acting siRNAs. This process is initiated by miRNA-directed and Argonaute (AGO) protein-mediated cleavage of TAS gene transcripts. One of the cleavage products is converted by RDR6 to double-stranded (ds)RNA, the substrate...

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Veröffentlicht in:	Nucleic acids research 2012-01, Vol.40 (2), p.594-599
Hauptverfasser:	Rajeswaran, Rajendran, Pooggin, Mikhail M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis - genetics Arabidopsis - metabolism Arabidopsis Proteins - metabolism DNA-directed RNA polymerase Double-stranded RNA Gene Regulation, Chromatin and Epigenetics MicroRNAs - metabolism miRNA Nucleotides RNA Replicase - metabolism RNA, Complementary - biosynthesis RNA, Complementary - chemistry RNA, Double-Stranded - metabolism RNA, Small Interfering - metabolism RNA-directed RNA polymerase Sequence Analysis, RNA siRNA tas gene Templates, Genetic Transcription
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