PET/MRI of Inflammation in Myocardial Infarction

Objectives The aim of this study was to explore post–myocardial infarction (MI) myocardial inflammation. Background Innate immune cells are centrally involved in infarct healing and are emerging therapeutic targets in cardiovascular disease; however, clinical tools to assess their presence in tissue...

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Veröffentlicht in:	Journal of the American College of Cardiology 2012-01, Vol.59 (2), p.153-163
Hauptverfasser:	Lee, Won Woo, MD, PhD, Marinelli, Brett, BA, van der Laan, Anja M., MD, Sena, Brena F., BS, Gorbatov, Rostic, BS, Leuschner, Florian, MD, Dutta, Partha, PhD, Iwamoto, Yoshiko, BS, Ueno, Takuya, MD, PhD, Begieneman, Mark P.V., BS, Niessen, Hans W.M., MD, PhD, Piek, Jan J., MD, PhD, Vinegoni, Claudio, PhD, Pittet, Mikael J., PhD, Swirski, Filip K., PhD, Tawakol, Ahmed, MD, Di Carli, Marcelo, MD, Weissleder, Ralph, MD, PhD, Nahrendorf, Matthias, MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Animals Apoptosis Biological and medical sciences Cardiology Cardiology. Vascular system Cardiovascular Case-Control Studies Coronary heart disease Female Flow cytometry Fluorodeoxyglucose F18 Glucose Heart Heart attacks Heart failure Humans inflammation Internal Medicine Ischemia Macrophages - physiology Magnetic Resonance Imaging Male Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Medical imaging Medical sciences Methods Mice Middle Aged Monocytes - physiology myocardial infarction Myocardial Infarction - diagnostic imaging Myocardial Infarction - enzymology Myocardial Infarction - immunology Myocarditis - diagnostic imaging Myocarditis - enzymology Myocarditis - immunology Myocarditis. Cardiomyopathies NMR Nuclear magnetic resonance PET/MRI Positron-Emission Tomography Radiopharmaceuticals remote myocardium Rodents Scanners Tomography
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