Age-Associated Deficits in Pattern Separation Functions of the Perirhinal Cortex: A Cross-Species Consensus

Normal aging causes a decline in object recognition. Importantly, lesions of the perirhinal cortex produce similar deficits and also lead to object discrimination impairments when the test objects share common features, suggesting that the perirhinal cortex participates in perceptual discrimination....

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Veröffentlicht in:	Behavioral neuroscience 2011-12, Vol.125 (6), p.836-847
Hauptverfasser:	Burke, Sarah N, Wallace, Jenelle L, Hartzell, Andrea L, Nematollahi, Saman, Plange, Kojo, Barnes, Carol A
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Differences Aging Aging - physiology Animal Animal cognition Animals Behavioral psychophysiology Biological and medical sciences Brain Cerebral Cortex - physiology Discrimination Learning - physiology Female Fundamental and applied biological sciences. Psychology Macaca radiata Male Maze Learning - physiology Monkeys Neurosciences Object Recognition Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Inbred F344 Recognition Recognition, Psychology - physiology Rodents Species Specificity
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