Central Corneal Thickness in Children
OBJECTIVES To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age and to determine whether CCT varies by age, race, or ethnicity. DESIGN Prospective observational multicenter study. Central corneal thickness was measur...
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| Veröffentlicht in: | Archives of ophthalmology (1960) 2011-09, Vol.129 (9), p.1132-1138 |
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| container_title | Archives of ophthalmology (1960) |
| container_volume | 129 |
| creator | Bradfield, Yasmin S Melia, B Michele Repka, Michael X Kaminski, Brett M Davitt, Bradley V Johnson, David A Kraker, Raymond T Manny, Ruth E Matta, Noelle S Weise, Katherine K Schloff, Susan |
| description | OBJECTIVES To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age and to determine whether CCT varies by age, race, or ethnicity. DESIGN Prospective observational multicenter study. Central corneal thickness was measured with a handheld contact pachymeter. RESULTS A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P |
| doi_str_mv | 10.1001/archophthalmol.2011.225 |
| format | Article |
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DESIGN Prospective observational multicenter study. Central corneal thickness was measured with a handheld contact pachymeter. RESULTS A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P < .001 for both) by approximately 20 μm. Thicker median CCT was observed with each successive year of age from age 1 to 11 years, with year-to-year differences steadily decreasing and reaching a plateau after age 11 at 573 μm in white and Hispanic children and 551 μm in African American children. For every 100 μm of thicker CCT measured, the intraocular pressure was 1.5 mm Hg higher on average (P < .001). For every diopter of increased myopic refractive error, CCT was 1 μm thinner on average (P < .001). CONCLUSIONS Median CCT increases with age from 1 to 11 years, with the greatest increase present in the youngest age groups. African American children on average have thinner central corneas than white and Hispanic children, whereas white and Hispanic children demonstrate similar CCT.</description><identifier>ISSN: 0003-9950</identifier><identifier>ISSN: 2168-6165</identifier><identifier>EISSN: 1538-3601</identifier><identifier>EISSN: 2168-6173</identifier><identifier>DOI: 10.1001/archophthalmol.2011.225</identifier><identifier>PMID: 21911662</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Adolescent ; Age differences ; Aging - physiology ; Biological and medical sciences ; Child ; Child, Preschool ; Cornea ; Cornea - anatomy & histology ; Diagnostic Techniques, Ophthalmological - instrumentation ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Medical sciences ; Miscellaneous ; Ophthalmology ; Pediatrics ; Prospective Studies ; Racial differences ; Racial Groups ; Reference Values</subject><ispartof>Archives of ophthalmology (1960), 2011-09, Vol.129 (9), p.1132-1138</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright American Medical Association Sep 2011</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a492t-39ee00bb706f4742da0cc43fff8ef6aae785f2c1123a6ed7f6152b4fd404d0fb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24570149$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21911662$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bradfield, Yasmin S</creatorcontrib><creatorcontrib>Melia, B Michele</creatorcontrib><creatorcontrib>Repka, Michael X</creatorcontrib><creatorcontrib>Kaminski, Brett M</creatorcontrib><creatorcontrib>Davitt, Bradley V</creatorcontrib><creatorcontrib>Johnson, David A</creatorcontrib><creatorcontrib>Kraker, Raymond T</creatorcontrib><creatorcontrib>Manny, Ruth E</creatorcontrib><creatorcontrib>Matta, Noelle S</creatorcontrib><creatorcontrib>Weise, Katherine K</creatorcontrib><creatorcontrib>Schloff, Susan</creatorcontrib><creatorcontrib>Pediatric Eye Disease Investigator Group</creatorcontrib><title>Central Corneal Thickness in Children</title><title>Archives of ophthalmology (1960)</title><addtitle>Arch Ophthalmol</addtitle><description>OBJECTIVES To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age and to determine whether CCT varies by age, race, or ethnicity. DESIGN Prospective observational multicenter study. Central corneal thickness was measured with a handheld contact pachymeter. RESULTS A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P < .001 for both) by approximately 20 μm. Thicker median CCT was observed with each successive year of age from age 1 to 11 years, with year-to-year differences steadily decreasing and reaching a plateau after age 11 at 573 μm in white and Hispanic children and 551 μm in African American children. For every 100 μm of thicker CCT measured, the intraocular pressure was 1.5 mm Hg higher on average (P < .001). For every diopter of increased myopic refractive error, CCT was 1 μm thinner on average (P < .001). CONCLUSIONS Median CCT increases with age from 1 to 11 years, with the greatest increase present in the youngest age groups. African American children on average have thinner central corneas than white and Hispanic children, whereas white and Hispanic children demonstrate similar CCT.</description><subject>Adolescent</subject><subject>Age differences</subject><subject>Aging - physiology</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Cornea</subject><subject>Cornea - anatomy & histology</subject><subject>Diagnostic Techniques, Ophthalmological - instrumentation</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Miscellaneous</subject><subject>Ophthalmology</subject><subject>Pediatrics</subject><subject>Prospective Studies</subject><subject>Racial differences</subject><subject>Racial Groups</subject><subject>Reference Values</subject><issn>0003-9950</issn><issn>2168-6165</issn><issn>1538-3601</issn><issn>2168-6173</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkU1P3DAQhq0KVLa0f6AHWCEhTtnO2I5jX5CqqKVISFzgbDmO3YQm9mLvVuq_x2i3UHoajeaZdz5eQk4RVgiAX0yyQ1wPm8FMc5xWFBBXlNbvyAJrJismAA_IAgBYpVQNR-RDzg8lFQjqPTmiqBCFoAty3rqwSWZatjEFV-LdMNpfweW8HMOyHcapTy58JIfeTNl92sdjcv_92137o7q5vbpuv95Uhiu6qZhyDqDrGhCeN5z2BqzlzHsvnRfGuEbWnlpEyoxwfeMF1rTjvufAe_AdOyaXO931tptdb3e76XUaZ5P-6GhG_bYSxkH_jL81ozUDikXgYi-Q4uPW5Y2ex2zdNJng4jZrKRXnspZNIc_-Ix_iNoVynZaKlj8BZwVqdpBNMefk_MsqCPrZCP3WCP1shC5GlM6Tfy956fv7-QKc7wGTrZl8MsGO-ZXjdQPIVeE-7zgzm9fpCEKCZE9lCp3m</recordid><startdate>20110901</startdate><enddate>20110901</enddate><creator>Bradfield, Yasmin S</creator><creator>Melia, B Michele</creator><creator>Repka, Michael X</creator><creator>Kaminski, Brett M</creator><creator>Davitt, Bradley V</creator><creator>Johnson, David A</creator><creator>Kraker, Raymond T</creator><creator>Manny, Ruth E</creator><creator>Matta, Noelle S</creator><creator>Weise, Katherine K</creator><creator>Schloff, Susan</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20110901</creationdate><title>Central Corneal Thickness in Children</title><author>Bradfield, Yasmin S ; Melia, B Michele ; Repka, Michael X ; Kaminski, Brett M ; Davitt, Bradley V ; Johnson, David A ; Kraker, Raymond T ; Manny, Ruth E ; Matta, Noelle S ; Weise, Katherine K ; Schloff, Susan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a492t-39ee00bb706f4742da0cc43fff8ef6aae785f2c1123a6ed7f6152b4fd404d0fb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Age differences</topic><topic>Aging - physiology</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Cornea</topic><topic>Cornea - anatomy & histology</topic><topic>Diagnostic Techniques, Ophthalmological - instrumentation</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Miscellaneous</topic><topic>Ophthalmology</topic><topic>Pediatrics</topic><topic>Prospective Studies</topic><topic>Racial differences</topic><topic>Racial Groups</topic><topic>Reference Values</topic><toplevel>online_resources</toplevel><creatorcontrib>Bradfield, Yasmin S</creatorcontrib><creatorcontrib>Melia, B Michele</creatorcontrib><creatorcontrib>Repka, Michael X</creatorcontrib><creatorcontrib>Kaminski, Brett M</creatorcontrib><creatorcontrib>Davitt, Bradley V</creatorcontrib><creatorcontrib>Johnson, David A</creatorcontrib><creatorcontrib>Kraker, Raymond T</creatorcontrib><creatorcontrib>Manny, Ruth E</creatorcontrib><creatorcontrib>Matta, Noelle S</creatorcontrib><creatorcontrib>Weise, Katherine K</creatorcontrib><creatorcontrib>Schloff, Susan</creatorcontrib><creatorcontrib>Pediatric Eye Disease Investigator Group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Archives of ophthalmology (1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bradfield, Yasmin S</au><au>Melia, B Michele</au><au>Repka, Michael X</au><au>Kaminski, Brett M</au><au>Davitt, Bradley V</au><au>Johnson, David A</au><au>Kraker, Raymond T</au><au>Manny, Ruth E</au><au>Matta, Noelle S</au><au>Weise, Katherine K</au><au>Schloff, Susan</au><aucorp>Pediatric Eye Disease Investigator Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central Corneal Thickness in Children</atitle><jtitle>Archives of ophthalmology (1960)</jtitle><addtitle>Arch Ophthalmol</addtitle><date>2011-09-01</date><risdate>2011</risdate><volume>129</volume><issue>9</issue><spage>1132</spage><epage>1138</epage><pages>1132-1138</pages><issn>0003-9950</issn><issn>2168-6165</issn><eissn>1538-3601</eissn><eissn>2168-6173</eissn><abstract>OBJECTIVES To determine the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age and to determine whether CCT varies by age, race, or ethnicity. DESIGN Prospective observational multicenter study. Central corneal thickness was measured with a handheld contact pachymeter. RESULTS A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P < .001 for both) by approximately 20 μm. Thicker median CCT was observed with each successive year of age from age 1 to 11 years, with year-to-year differences steadily decreasing and reaching a plateau after age 11 at 573 μm in white and Hispanic children and 551 μm in African American children. For every 100 μm of thicker CCT measured, the intraocular pressure was 1.5 mm Hg higher on average (P < .001). For every diopter of increased myopic refractive error, CCT was 1 μm thinner on average (P < .001). CONCLUSIONS Median CCT increases with age from 1 to 11 years, with the greatest increase present in the youngest age groups. African American children on average have thinner central corneas than white and Hispanic children, whereas white and Hispanic children demonstrate similar CCT.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>21911662</pmid><doi>10.1001/archophthalmol.2011.225</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Age differences Aging - physiology Biological and medical sciences Child Child, Preschool Cornea Cornea - anatomy & histology Diagnostic Techniques, Ophthalmological - instrumentation Female Humans Infant Infant, Newborn Male Medical sciences Miscellaneous Ophthalmology Pediatrics Prospective Studies Racial differences Racial Groups Reference Values |
| title | Central Corneal Thickness in Children |
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