Dynamic contrast-enhanced MR imaging findings of bone metastasis in patients with prostate cancer

Dynamic contrast-enhanced MR imaging findings of bone metastasis in patients with prostate cancer

AIM:To evaluate the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) findings of bone metastasis in prostate cancer patients.METHODS:Sixteen men with a diagnosis of metastatic prostate cancer to bones were examined with DCE-MRI at 1.5 Tesla.The mean contrast agent concentration vs time...

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Veröffentlicht in:World journal of radiology 2011-10, Vol.3 (10), p.241-245
Hauptverfasser: Kayhan, Arda, Yang, Cheng, Soylu, Fatma Nur, Lakadamyalı, Hatice, Sethi, Ila, Karczmar, Gregory, Stadler, Walter, Oto, Aytekin
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Sprache:eng
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Bone
Brief
Cancer
contrast-enhanced
Dynamic
imaging
Metastasis
Prostate
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container_end_page 245
container_issue 10
container_start_page 241
container_title World journal of radiology
container_volume 3
creator Kayhan, Arda
Yang, Cheng
Soylu, Fatma Nur
Lakadamyalı, Hatice
Sethi, Ila
Karczmar, Gregory
Stadler, Walter
Oto, Aytekin
description AIM:To evaluate the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) findings of bone metastasis in prostate cancer patients.METHODS:Sixteen men with a diagnosis of metastatic prostate cancer to bones were examined with DCE-MRI at 1.5 Tesla.The mean contrast agent concentration vs time curves for bone metastasis and normal bone were calculated and K trans and ve values were estimated and compared.RESULTS:An early significant enhancement (wash-out:n=6,plateau:n=8 and persistent:n=2) was detected in all bone metastases (n=16).Bone metastasis from prostate cancer showed significant enhancementand high K trans and ve values compared to normal bone which does not enhance in the elderly population.The mean K trans was 0.101/mmiinn and 0.0051/mmiinn (P < 0.001),the mean ve was 0.141 and 0.0038 (P < 0.001),for bone metastases and normal bone,respectively.
doi_str_mv 10.4329/wjr.v3.i10.241
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source Baishideng "World Journal of" online journals; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Bone
Brief
Cancer
contrast-enhanced
Dynamic
imaging
Metastasis
Prostate
title Dynamic contrast-enhanced MR imaging findings of bone metastasis in patients with prostate cancer
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