Development of responder definitions for fibromyalgia clinical trials

Objective To develop responder definitions for fibromyalgia (FM) clinical trials using key symptom and function domains. Methods Twenty‐four candidate responder definitions were developed by expert consensus and were evaluated in 12 randomized, placebo‐controlled trials of 4 medications for the trea...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2012-03, Vol.64 (3), p.885-894
Hauptverfasser:	Arnold, Lesley M., Williams, David A., Hudson, James I., Martin, Susan A., Clauw, Daniel J., Crofford, Leslie J., Wang, Fujun, Emir, Birol, Lai, Chinglin, Zablocki, Rong, Mease, Philip J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Clinical trials Confidence intervals Diseases of the osteoarticular system Endpoint Determination Fibromyalgia Fibromyalgia - diagnosis Fibromyalgia - drug therapy Fibromyalgia - physiopathology Humans Medical sciences Meta-Analysis as Topic Miscellaneous. Osteoarticular involvement in other diseases Outcome Assessment (Health Care) Pain - physiopathology Pain Management Pain Measurement Pain Threshold Placebo Effect Recovery of Function
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