Short-lived immunity against pertussis, age-specific routes of transmission, and the utility of a teenage booster vaccine

Highlights ► Immunity against pertussis is relatively short-lived and heterogeneous. ► Vaccination prevents both disease and transmission. ► The age-mixing patterns lead to little contact between teenagers and infants. ► A teenage booster vaccine will not likely indirectly protect infants.

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Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2012-01, Vol.30 (3), p.544-551
Hauptverfasser:	Lavine, Jennie S, Bjørnstad, Ottar N, de Blasio, Birgitte Freiesleben, Storsaeter, Jann
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent adolescents Adult Age Aged Aged, 80 and over Allergy and Immunology case studies Child Child, Preschool childhood Confidence intervals data collection Disease transmission Epidemiology Estimates Female Humans Hypotheses immunity Immunization, Secondary - methods Incidence Infant Infant, Newborn Infants Male Middle Aged Norway Norway - epidemiology Pertussis Vaccine - administration & dosage Pertussis Vaccine - immunology Public health risk school children Teenagers vaccination Vaccines Vaccines, Acellular - administration & dosage Vaccines, Acellular - immunology Whooping Cough - epidemiology Whooping Cough - immunology Whooping Cough - prevention & control Whooping Cough - transmission Young Adult
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Beschreibung
Zusammenfassung:	Highlights ► Immunity against pertussis is relatively short-lived and heterogeneous. ► Vaccination prevents both disease and transmission. ► The age-mixing patterns lead to little contact between teenagers and infants. ► A teenage booster vaccine will not likely indirectly protect infants.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2011.11.065