Early onset of fatty liver in growth-restricted rat fetuses and newborns

ABSTRACT Intrauterine growth‐restricted (IUGR) newborns have increased risk of adult metabolic syndrome, including fatty liver. However, it is unclear whether the fatty liver development is “programmed” or secondary to the accompanying obesity. In this study, we examined hepatic lipid accumulation a...

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Veröffentlicht in:	Congenital anomalies 2011-12, Vol.51 (4), p.167-173
Hauptverfasser:	Yamada, Makiko, Wolfe, Diana, Han, Guang, French, Samuel W., Ross, Michael G., Desai, Mina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Electron Microscope Tomography fatty acid synthase fatty liver Fatty Liver - embryology Fatty Liver - metabolism Female Fetal Growth Retardation - metabolism Fetus - metabolism intrauterine growth retardation Liver - embryology Liver - growth & development Liver - metabolism Pregnancy programming Rats Rats, Sprague-Dawley sterol regulatory element-binding protein 1 Up-Regulation
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