Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers

Multicomponent reactions are employed extensively in many areas of organic chemistry. Despite significant progress, the discovery of such enabling transformations remains challenging. Here, we present the development of a parallel, label-free reaction-discovery platform that can be used in the ident...

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Veröffentlicht in:Nature chemistry 2012-01, Vol.4 (1), p.45-51
Hauptverfasser: Montavon, Timothy J., Li, Jing, Cabrera-Pardo, Jaime R., Mrksich, Milan, Kozmin, Sergey A.
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Sprache:eng
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