Differential pattern of glycogen accumulation after protein phosphatase 1 glycogen-targeting subunit PPP1R6 overexpression, compared to PPP1R3C and PPP1R3A, in skeletal muscle cells

PPP1R6 is a protein phosphatase 1 glycogen-targeting subunit (PP1-GTS) abundant in skeletal muscle with an undefined metabolic control role. Here PPP1R6 effects on myotube glycogen metabolism, particle size and subcellular distribution are examined and compared with PPP1R3C/PTG and PPP1R3A/G(M). PPP...

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Veröffentlicht in:	BMC biochemistry 2011-11, Vol.12 (1), p.57-57
Hauptverfasser:	Montori-Grau, Marta, Guitart, Maria, García-Martínez, Cèlia, Orozco, Anna, Gómez-Foix, Anna Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Animals Aparell locomotor Carrier Proteins - genetics Carrier Proteins - metabolism Cytosol - metabolism Diabetes Enzymes ErbB Receptors - genetics ErbB Receptors - metabolism Expressió gènica Fatty acids Fetge Gene expression Gene Expression Regulation Genetic aspects Genetic regulation Glicogen Glycogen Glycogen - biosynthesis Glycogen - metabolism Glycogen - ultrastructure Glycogen Phosphorylase - metabolism HEK293 Cells Humans Liver Metabolic regulation Metabolism Metabolisme Mice Microfilament Proteins - genetics Microfilament Proteins - metabolism Muscle cells Muscle Fibers, Skeletal - metabolism Muscle Fibers, Skeletal - ultrastructure Muscle, Skeletal - cytology Muscle, Skeletal - ultrastructure Muscular system Musculoskeletal system Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Phosphatases Phosphoprotein Phosphatases - genetics Phosphoprotein Phosphatases - metabolism Phosphorylation Physiological aspects Proteins Regulació del metabolisme Regulació genètica Rodents Signal Transduction Àcids grassos
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