A Data Processing Pipeline for Mammalian Proteome Dynamics Studies Using Stable Isotope Metabolic Labeling

In a recent study, in vivo metabolic labeling using 15N traced the rate of label incorporation among more than 1700 proteins simultaneously and enabled the determination of individual protein turnover rate constants over a dynamic range of three orders of magnitude (Price, J. C., Guan, S., Burlingam...

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Veröffentlicht in:Molecular & cellular proteomics 2011-12, Vol.10 (12), p.M111.010728-M111.010728, Article M111.010728
Hauptverfasser: Guan, Shenheng, Price, John C., Prusiner, Stanley B., Ghaemmaghami, Sina, Burlingame, Alma L.
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Sprache:eng
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