Attenuating GABAA Receptor Signaling in Dopamine Neurons Selectively Enhances Reward Learning and Alters Risk Preference in Mice

Phasic dopamine (DA) transmission encodes the value of reward-predictive stimuli and influences both learning and decision-making. Altered DA signaling is associated with psychiatric conditions characterized by risky choices such as pathological gambling. These observations highlight the importance...

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Veröffentlicht in:	The Journal of neuroscience 2011-11, Vol.31 (47), p.17103-17112
Hauptverfasser:	Parker, Jones G., Wanat, Matthew J., Soden, Marta E., Ahmad, Kinza, Zweifel, Larry S., Bamford, Nigel S., Palmiter, Richard D.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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