Regulation of intrahepatic biliary duct morphogenesis by Claudin 15-like b

The intrahepatic biliary ducts transport bile produced by the hepatocytes out of the liver. Defects in biliary cell differentiation and biliary duct remodeling cause a variety of congenital diseases including Alagille Syndrome and polycystic liver disease. While the molecular pathways regulating bil...

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Veröffentlicht in:	Developmental biology 2012-01, Vol.361 (1), p.68-78
Hauptverfasser:	Cheung, Isla D., Bagnat, Michel, Ma, Taylur P., Datta, Anirban, Evason, Kimberley, Moore, John C., Lawson, Nathan D., Mostov, Keith E., Moens, Cecilia B., Stainier, Didier Y.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	abnormal development Animals bile Bile Ducts, Intrahepatic - cytology Bile Ducts, Intrahepatic - growth & development Bile Ducts, Intrahepatic - metabolism Biliary cells Biliary duct morphogenesis Biliary duct remodeling cell differentiation Cell Line Cell Polarity - physiology Cholestasis Claudin Claudins - genetics Claudins - metabolism Danio rerio Dogs epithelial cells Epithelial Cells - metabolism Fluorescent Antibody Technique genes hepatocytes Hepatocytes - metabolism In Situ Hybridization Larva - growth & development Larva - metabolism liver Liver development liver diseases Microscopy, Electron, Transmission morphogenesis Morphogenesis - physiology mutants Mutation - genetics proteins Tight junctions Tight Junctions - metabolism Zebrafish Zebrafish - growth & development Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism
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