Post-transcriptional regulation of heparanase gene expression by a 3' AU-rich element

Heparanase up-regulation was documented in an increasing number of human carcinomas, associated with poor prognosis. The purpose of the current study was to identify mechanisms responsible for heparanase induction. We provide evidence that heparanase expression is regulated at the post-transcription...

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Veröffentlicht in:	The FASEB journal 2010-12, Vol.24 (12), p.4969-4976
Hauptverfasser:	Arvatz, Gil, Barash, Uri, Nativ, Ofer, Ilan, Neta, Vlodavsky, Israel
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics Blotting, Western Cell Line Cell Line, Tumor Gene Expression Regulation - genetics Glucuronidase - genetics Glucuronidase - metabolism Humans Research Communications RNA Stability - genetics RNA, Messenger - genetics
Online-Zugang:	Volltext
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