Engineered Nanostructures of Antigen Provide an Effective Means for Regulating Mast Cell Activation

Nanostructures containing 2,4-dinitrophenyl (DNP) as antigen were designed and produced to investigate antibody-mediated activation of mast cells. The design consists of nanogrids of DNP termini inlaid in alkanethiol self-assembled monolayers (SAMs). Using scanning probe-based nanografting, nanomete...

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Veröffentlicht in:	ACS nano 2011-11, Vol.5 (11), p.8672-8683
Hauptverfasser:	Deng, Zhao, Weng, I-Chun, Li, Jie-Ren, Chen, Huan-Yuan, Liu, Fu-Tong, Liu, Gang-yu
Format:	Artikel
Sprache:	eng
Schlagworte:	2,4-Dinitrophenol - chemistry Activation Adhesion Animals Antibodies - immunology Antigen Presentation - immunology Antigens Cascades Cell Adhesion - immunology Cell Line, Tumor Cellular Clustering Haptens - chemistry Haptens - immunology Mast Cells - cytology Mast Cells - immunology Masts Nanostructure Nanostructures - chemistry Nanotechnology Rats Signal Transduction - immunology Spreading
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