Monitoring Equilibrium Changes in RNA Structure by 'Peroxidative' and 'Oxidative' Hydroxyl Radical Footprinting

RNA molecules play an essential role in biology. In addition to transmitting genetic information, RNA can fold into unique tertiary structures fulfilling a specific biologic role as regulator, binder or catalyst. Information about tertiary contact formation is essential to understand the function of...

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Veröffentlicht in:	Journal of Visualized Experiments 2011-10 (56), p.e3244
Hauptverfasser:	Bachu, Ravichandra, Padlan, Frances-Camille S., Rouhanifard, Sara, Brenowitz, Michael, Schlatterer, Jörg C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cations, Divalent - chemistry Hydrogen Peroxide - chemistry Hydroxyl Radical - chemistry Kinetics Magnesium - chemistry Molecular Biology Nucleic Acid Conformation Oxidation-Reduction Peroxides - chemistry RNA - chemistry RNA, Catalytic - chemistry Tetrahymena - enzymology
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