Activation of human vascular cells decreases their expression of transforming growth factor-beta

Abstract Objective Despite pro-fibrotic effects, transforming growth factor (TGF)-β prevents arteriosclerosis by suppressing effector leukocytes and promoting smooth muscle differentiation. However, previous observations of increased TGF-β expression in arteriosclerotic plaques are not consistent wi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Atherosclerosis 2011-12, Vol.219 (2), p.417-424
Hauptverfasser:	Lebastchi, Amir H, Qin, Lingfeng, Khan, Salman F, Zhou, Jing, Geirsson, Arnar, Kim, Richard W, Li, Wei, Tellides, George
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis Apoptosis - drug effects Arteriosclerosis atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Calcium Ionophores - pharmacology Cardiology. Vascular system Cardiovascular Case-Control Studies Cells, Cultured Coronary Artery Disease - immunology Coronary Artery Disease - metabolism Coronary Artery Disease - pathology Coronary Artery Disease - prevention & control coronary vessels Coronary Vessels - drug effects Coronary Vessels - metabolism Down-Regulation endothelial cells Endothelial Cells - drug effects Endothelial Cells - immunology Endothelial Cells - metabolism Endothelial Cells - pathology fibroblasts Human Human Umbilical Vein Endothelial Cells - drug effects Human Umbilical Vein Endothelial Cells - metabolism Humans inflammation interleukin-11 Interleukin-11 - metabolism Ionomycin - pharmacology leukocytes Leukocytes - drug effects Leukocytes - immunology Medical sciences Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - immunology Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology myocytes Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - immunology Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology organ culture Organ Culture Techniques Recombinant Proteins - metabolism Signal Transduction - drug effects smooth muscle Smooth muscle cells Tetradecanoylphorbol Acetate - pharmacology Time Factors transforming growth factor beta Transforming Growth Factor beta1 - metabolism Transforming growth factor-β
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!