Enhanced Intestinal Absorption of Daidzein by Borneol/Menthol Eutectic Mixture and Microemulsion

In the present study, the effect of a borneol/menthol eutectic mixture (25:75) and microemulsion on the absorption of daidzein in rat intestinal membrane was evaluated. The microemulsion formulation was composed of ethyl oleate (oil), Cremophor RH40 (surfactant), PEG400 (co-surfactant), and water. T...

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Veröffentlicht in:	AAPS PharmSciTech 2011-12, Vol.12 (4), p.1044-1049
Hauptverfasser:	Shen, Qi, Li, Xi, Li, Wenji, Zhao, Xinyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism Biochemistry Biological Availability Biomedical and Life Sciences Biomedicine Biotechnology Bornanes - administration & dosage Bornanes - chemistry Bornanes - pharmacology Chemistry, Pharmaceutical Dose-Response Relationship, Drug Drug Compounding Emulsions Indexing in process Intestinal Absorption - drug effects Intestines - drug effects Intestines - metabolism Isoflavones - administration & dosage Isoflavones - chemistry Isoflavones - pharmacokinetics Male Methanol - administration & dosage Methanol - chemistry Methanol - pharmacology Oils - chemistry Oleic Acids - chemistry Pharmacology/Toxicology Pharmacy Polyethylene Glycols - chemistry Rats Rats, Sprague-Dawley Research Article Solubility Surface-Active Agents - chemistry Technology, Pharmaceutical Verapamil - pharmacology Water - chemistry
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