Characterization of Novel Leishmania infantum Recombinant Proteins Encoded by Genes from Five Families with Distinct Capacities for Serodiagnosis of Canine and Human Visceral Leishmaniasis

To expand the available panel of recombinant proteins that can be useful for identifying Leishmania-infected dogs and for diagnosing human visceral leishmaniasis (VL), we selected recombinant antigens from L. infantum, cDNA, and genomic libraries by using pools of serum samples from infected dogs an...

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Veröffentlicht in:	The American journal of tropical medicine and hygiene 2011-12, Vol.85 (6), p.1025-1034
Hauptverfasser:	OLIVEIRA, Geraldo G. S, MAGALHAES, Franklin B, GOMES, Yara M, MOREIRA, Edson D, BRITO, Maria E. F, PONTES DE CARVALHO, Lain C, DE MELO, Osvaldo P, TEIXEIRA, Márcia C. A, PEREIRA, Andrea M, PINHEIRO, Cristiane G. M, SANTOS, Lenita R, NASCIMENTO, Marilia B, BEDOR, Cheila N. G, ALBUQUERQUE, Alessandra L, DOS-SANTOS, Washington L. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Protozoan - genetics Biological and medical sciences Cloning, Molecular Dog Diseases - diagnosis Dog Diseases - parasitology Dogs Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - veterinary Genes, Protozoan - genetics HSP70 Heat-Shock Proteins - genetics Human protozoal diseases Humans Infectious diseases Kinesin - genetics Leishmania infantum Leishmania infantum - genetics Leishmaniasis, Visceral - diagnosis Leishmaniasis, Visceral - parasitology Leishmaniasis, Visceral - veterinary Leshmaniasis Medical sciences Parasitic diseases Polyubiquitin - genetics Protozoal diseases Recombinant Proteins - genetics Sensitivity and Specificity Serologic Tests - methods Serologic Tests - veterinary
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