Expression of genes of the aflatoxin biosynthetic pathway in Aspergillus flavus isolates from keratitis

To document transcriptional activation (expression) of key aflatoxin biosynthetic pathway genes in corneal isolates of Aspergillus flavus. The expression of certain regulatory (aflatoxin regulatory [aflR] and aflatoxin J [aflJ]) and structural (polyketide synthase acetate [pksA] and norsolonic acid-...

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Veröffentlicht in:	Molecular vision 2011, Vol.17, p.2889-2897
Hauptverfasser:	Leema, George, Chou, Duen-Suey, Jesudasan, Christadoss A Nelson, Geraldine, Pitchairaj, Thomas, Philip A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic acid Aflatoxins Aflatoxins - biosynthesis Aflatoxins - genetics Aspergillus flavus Aspergillus flavus - genetics Aspergillus flavus - isolation & purification Aspergillus flavus - metabolism Biosynthetic Pathways - genetics Chromatography, Thin Layer Cornea Cornea - microbiology Cornea - pathology DNA-Binding Proteins - biosynthesis DNA-Binding Proteins - genetics Fungal Proteins - biosynthesis Fungal Proteins - genetics Gene Expression Regulation, Fungal Genes, Fungal Humans Keratitis Keratitis - microbiology Keratitis - pathology Microenvironments Polyketide synthase Polyketide Synthases - biosynthesis Polyketide Synthases - genetics Polymerase Chain Reaction Reverse transcription Spectrophotometry Thin-layer chromatography Transcription activation Transcription Factors - biosynthesis Transcription Factors - genetics Transcriptional Activation Vision
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