The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology
The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments a...
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Veröffentlicht in: | Bioinformatics 2011-12, Vol.27 (23), p.3323-3324 |
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container_title | Bioinformatics |
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creator | Blakes, Jonathan Twycross, Jamie Romero−Campero, Francisco Jose Krasnogor, Natalio |
description | The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking.
Availability: Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3.
Contact:
Natalio.Krasnogor@nottingham.ac.uk |
doi_str_mv | 10.1093/bioinformatics/btr571 |
format | Article |
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Availability: Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3.
Contact:
Natalio.Krasnogor@nottingham.ac.uk</description><identifier>ISSN: 1367-4803</identifier><identifier>EISSN: 1460-2059</identifier><identifier>EISSN: 1367-4811</identifier><identifier>DOI: 10.1093/bioinformatics/btr571</identifier><identifier>PMID: 21994219</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Algorithms ; Applications Note ; Biological and medical sciences ; Computer Simulation ; Fundamental and applied biological sciences. Psychology ; General aspects ; Humans ; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) ; Models, Biological ; Models, Statistical ; Programming Languages ; Software ; Synthetic Biology ; Systems Biology</subject><ispartof>Bioinformatics, 2011-12, Vol.27 (23), p.3323-3324</ispartof><rights>The Author(s) 2011. Published by Oxford University Press. 2011</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c513t-abfe558e4ff49775f67a5556e7249528360fa8465c5a7873f7d9fe68d899cc8d3</citedby><cites>FETCH-LOGICAL-c513t-abfe558e4ff49775f67a5556e7249528360fa8465c5a7873f7d9fe68d899cc8d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223367/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223367/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,1599,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=25232413$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21994219$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Blakes, Jonathan</creatorcontrib><creatorcontrib>Twycross, Jamie</creatorcontrib><creatorcontrib>Romero−Campero, Francisco Jose</creatorcontrib><creatorcontrib>Krasnogor, Natalio</creatorcontrib><title>The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology</title><title>Bioinformatics</title><addtitle>Bioinformatics</addtitle><description>The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking.
Availability: Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3.
Contact:
Natalio.Krasnogor@nottingham.ac.uk</description><subject>Algorithms</subject><subject>Applications Note</subject><subject>Biological and medical sciences</subject><subject>Computer Simulation</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Humans</subject><subject>Mathematics in biology. Statistical analysis. Models. Metrology. 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Psychology</topic><topic>General aspects</topic><topic>Humans</topic><topic>Mathematics in biology. Statistical analysis. Models. Metrology. 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Availability: Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3.
Contact:
Natalio.Krasnogor@nottingham.ac.uk</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>21994219</pmid><doi>10.1093/bioinformatics/btr571</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford Journals Open Access Collection; PubMed Central; Alma/SFX Local Collection |
subjects | Algorithms Applications Note Biological and medical sciences Computer Simulation Fundamental and applied biological sciences. Psychology General aspects Humans Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Models, Biological Models, Statistical Programming Languages Software Synthetic Biology Systems Biology |
title | The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology |
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