The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology

The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments a...

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Veröffentlicht in:Bioinformatics 2011-12, Vol.27 (23), p.3323-3324
Hauptverfasser: Blakes, Jonathan, Twycross, Jamie, Romero−Campero, Francisco Jose, Krasnogor, Natalio
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container_end_page 3324
container_issue 23
container_start_page 3323
container_title Bioinformatics
container_volume 27
creator Blakes, Jonathan
Twycross, Jamie
Romero−Campero, Francisco Jose
Krasnogor, Natalio
description The Infobiotics Workbench is an integrated software suite incorporating model specification, simulation, parameter optimization and model checking for Systems and Synthetic Biology. A modular model specification allows for straightforward creation of large-scale models containing many compartments and reactions. Models are simulated either using stochastic simulation or numerical integration, and visualized in time and space. Model parameters and structure can be optimized with evolutionary algorithms, and model properties calculated using probabilistic model checking. Availability: Source code and binaries for Linux, Mac and Windows are available at http://www.infobiotics.org/infobiotics-workbench/; released under the GNU General Public License (GPL) version 3. Contact: Natalio.Krasnogor@nottingham.ac.uk
doi_str_mv 10.1093/bioinformatics/btr571
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford Journals Open Access Collection; PubMed Central; Alma/SFX Local Collection
subjects Algorithms
Applications Note
Biological and medical sciences
Computer Simulation
Fundamental and applied biological sciences. Psychology
General aspects
Humans
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Models, Biological
Models, Statistical
Programming Languages
Software
Synthetic Biology
Systems Biology
title The Infobiotics Workbench: an integrated in silico modelling platform for Systems and Synthetic Biology
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