Expression of heat shock protein 47 is increased in remnant kidney and correlates with disease progression

Glomerulosclerosis is characterized by accumulation of the mesangial extracellular matrix, including type I and IV collagen. The processing for the collagens in the glomeruli may play a critical role for development of glomerulosclerosis. We examined the expression of heat shock protein 47 (HSP47),...

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Veröffentlicht in:	International journal of experimental pathology 1998-06, Vol.79 (3), p.133-140
Hauptverfasser:	SUNAMOTO, MASAAKI, KUZE, KOGO, IEHARA, NORIYUKI, TAKEOKA, HIROYA, NAGATA, KAZUHIRO, KITA, TORU, DOI, TOSHIO
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Western Collagen - genetics Collagen - metabolism collagens Disease Progression Extracellular Matrix - pathology Fluorescent Antibody Technique Gene Expression Glomerulonephritis glomerulosclerosis Glomerulosclerosis, Focal Segmental - etiology Glomerulosclerosis, Focal Segmental - metabolism Glomerulosclerosis, Focal Segmental - pathology heat shock proteins Heat-Shock Proteins - metabolism HSP47 Heat-Shock Proteins In Situ Hybridization Kidney - metabolism Male Medical sciences Nephrectomy Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Rats Rats, Wistar RNA, Messenger - genetics
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