Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation

Inflammation during mechanical ventilation is thought to depend on regional mechanical stress. This can be produced by concentration of stresses and cyclic recruitment in low-aeration dependent lung. Positron emission tomography (PET) with (18)F-fluorodeoxyglucose ((18)F-FDG) allows for noninvasive...

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Veröffentlicht in:	Journal of applied physiology (1985) 2011-11, Vol.111 (5), p.1249-1258
Hauptverfasser:	DE PROST, Nicolas, COSTA, Eduardo L, WELLMAN, Tyler, MUSCH, Guido, WINKLER, Tilo, TUCCI, Mauro R, HARRIS, R. Scott, VENEGAS, Jose G, VIDAL MELO, Marcos F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bronchoalveolar Lavage - methods Fluorodeoxyglucose F18 - pharmacokinetics Fundamental and applied biological sciences. Psychology Glucose Inflammation - diagnostic imaging Inflammation - drug therapy Inflammation - metabolism Lung - diagnostic imaging Lung - metabolism Lungs Metabolism Nitrogen Radioisotopes - administration & dosage Positive-Pressure Respiration - methods Positron-Emission Tomography - methods Pulmonary Surfactants - metabolism Radiopharmaceuticals - pharmacokinetics Respiration, Artificial - methods Sheep Stress, Mechanical Tomography Ventilation
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