More on FOX News: FOXA1 on the horizon of estrogen receptor function and endocrine response

Estrogen receptor α (ER) is a major driver of breast cancer and the target of endocrine therapy. Full disclosure of the cofactors regulating ER interactions with chromatin and its transcriptional regulatory activity is still elusive. Novel genome-wide profiling tools have mapped ER binding events in...

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Veröffentlicht in:	Breast cancer research : BCR 2011-04, Vol.13 (2), p.307-307, Article 307
Hauptverfasser:	Fu, Xiaoyong, Huang, Catherine, Schiff, Rachel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Hormonal - therapeutic use Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - metabolism Cell Line, Tumor Cell Proliferation - drug effects Chromatin Chromatin - metabolism Estrogens Female Genome-Wide Association Study Genomes Genomics Hepatocyte Nuclear Factor 3-alpha - genetics Hepatocyte Nuclear Factor 3-alpha - metabolism Humans Phenols (Class of compounds) Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Tamoxifen Tamoxifen - therapeutic use Transcription (Genetics) Transcription, Genetic Viewpoint
Online-Zugang:	Volltext
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