The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs

Human liver cDNA coding for protein C has been synthesized, cloned and sequenced. The abundance of protein C message is approximately 0.02% of total mRNA. Three overlapping clones contain 1,798 nucleotides of contiguous sequence, which approximates the size of the protein's mRNA, based upon Nor...

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Veröffentlicht in:	Nucleic acids research 1985-07, Vol.13 (14), p.5233-5247
Hauptverfasser:	Beckmann, Robert J., Schmidt, Robert J., Santerre, Robert F., Plutzky, Jorge, Crabtree, Gerald R., Long, George L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Base Sequence Biological and medical sciences cDNA Deoxyribonuclease BamHI Deoxyribonucleases, Type II Site-Specific DNA - analysis DNA Restriction Enzymes - metabolism Factor IX - analysis Factor X - analysis Fundamental and applied biological sciences. Psychology Glycoproteins - biosynthesis Humans liver Miscellaneous Molecular and cellular biology Molecular genetics mRNA Nucleic Acid Hybridization nucleotide sequence Protein C Protein Precursors - genetics Prothrombin - analysis RNA, Messenger - analysis
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