Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA

Pre-mRNA splicing deposits multi-protein complexes, termed exon junction complexes (EJCs), on mRNAs near exon-exon junctions. The core of EJC consists of four proteins, eIF4AIII, MLN51, Y14 and Magoh. Y14 is a nuclear protein that can shuttle between the nucleus and the cytoplasm and binds specifica...

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Veröffentlicht in:	Scientific reports 2011-09, Vol.1 (1), p.92-92, Article 92
Hauptverfasser:	Kataoka, Naoyuki, Diem, Michael D., Yoshida, Mayumi, Hatai, Chihiro, Dobashi, Izumi, Dreyfuss, Gideon, Hagiwara, Masatoshi, Ohno, Mutsuhito
Format:	Artikel
Sprache:	eng
Schlagworte:	631/1647 631/326 631/45 631/80 Amino Acid Sequence Biochemistry Biology Cell Nucleus - metabolism Cytoplasm Cytoplasm - metabolism Exons Gene expression HeLa Cells Humanities and Social Sciences Humans Insects Kinases Localization Molecular Sequence Data Monoclonal antibodies mRNA multidisciplinary Nuclear Export Signals Nuclear transport Peptides Protein Transport Proteins RNA Splicing RNA, Messenger - metabolism RNA-Binding Proteins - chemistry RNA-Binding Proteins - metabolism Science Splicing
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