AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin

Adiponectin can act in the brain to increase energy expenditure and reduce body weight by mechanisms not entirely understood. We found that adiponectin type 1 and type 2 receptors (AdipoR1 and AdipoR2) are expressed in warm sensitive neurons of the hypothalamic preoptic area (POA) which play a criti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2011-11, Vol.1423, p.1-9
Hauptverfasser:	Klein, Izabella, Sanchez-Alavez, Manuel, Tabarean, Iustin, Schaefer, Jean, Holmberg, Kristina H, Klaus, Joe, Xia, Fengcheng, Marcondes, Maria Cecilia Garibaldi, Dubins, Jeffrey S, Morrison, Brad, Zhukov, Viktor, Sanchez-Gonzalez, Alejandro, Mitsukawa, Kayo, Hadcock, John R, Bartfai, Tamas, Conti, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adiponectin - pharmacology Adiponectin receptor Analysis of Variance Animals body temperature Body Temperature - drug effects body weight Calorimetry, Indirect carbohydrates energy expenditure Energy Metabolism - drug effects Gene Expression Regulation - drug effects Gene Expression Regulation - genetics Homeostasis In Vitro Techniques Male Mice Mice, Inbred C57BL Mice, Knockout Neurology neurons oxidation Preoptic area Preoptic Area - cytology receptors Receptors, Adiponectin - deficiency Receptors, Adiponectin - metabolism Sensory Receptor Cells - drug effects Sensory Receptor Cells - physiology Telemetry Temperature Thermosensing - drug effects Thermosensing - physiology Warm sensitive neuron
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!