Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis

Rationale The risk of pulmonary exacerbation following Pseudomonas aeruginosa (Pa) acquisition in children with cystic fibrosis (CF) is unknown. Objectives To determine if failure of antibiotic therapy to eradicate Pa and frequency of Pa recurrence are associated with increased exacerbation risk. Me...

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Veröffentlicht in:	Pediatric pulmonology 2012-02, Vol.47 (2), p.125-134
Hauptverfasser:	Mayer-Hamblett, Nicole, Kronmal, Richard A., Gibson, Ronald L., Rosenfeld, Margaret, Retsch-Bogart, George, Treggiari, Miriam M., Burns, Jane L., Khan, Umer, Ramsey, Bonnie W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - therapeutic use Biological and medical sciences Child Child, Preschool Ciprofloxacin - therapeutic use clinical outcome Cystic Fibrosis - drug therapy Cystic Fibrosis - microbiology early intervention eradication Errors of metabolism Female General aspects Humans Male Medical sciences Metabolic diseases Miscellaneous hereditary metabolic disorders new acquisition Pneumology Pseudomonas aeruginosa - drug effects Pseudomonas Infections - drug therapy Recurrence Risk Tobramycin - therapeutic use Treatment Failure
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