Effects of weight loss and leptin on skeletal muscle in human subjects

Maintenance of a 10% or greater reduced body weight results in decreases in the energy cost of low levels of physical activity beyond those attributable to the altered body weight. These changes in nonresting energy expenditure are due mainly to increased skeletal muscle work efficiency following we...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2011-11, Vol.301 (5), p.R1259-R1266
Hauptverfasser:	Baldwin, Kenneth M, Joanisse, Denis R, Haddad, Fadia, Goldsmith, Rochelle L, Gallagher, Dympna, Pavlovich, Katherine H, Shamoon, Elisabeth L, Leibel, Rudolph L, Rosenbaum, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Adiposity Analysis of Variance Biopsy Call for Papers Cross-Over Studies Effects Energy Metabolism - drug effects Female Gene expression Gene Expression Regulation Humans Injections, Subcutaneous Leptin - administration & dosage Male Muscle Contraction - drug effects Muscle Strength - drug effects Musculoskeletal system Myosin Heavy Chains - genetics Obesity - diet therapy Obesity - genetics Obesity - metabolism Obesity - pathology Obesity - physiopathology Proteins Quadriceps Muscle - drug effects Quadriceps Muscle - metabolism Quadriceps Muscle - pathology Quadriceps Muscle - physiopathology RNA, Messenger - metabolism Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics Single-Blind Method Time Factors Treatment Outcome Weight control Weight Loss
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