Characterization of upper thoracic spinal neurons receiving noxious cardiac and/or somatic inputs in diabetic rats

Abstract The aim of the present study was to examine spinal processing of cardiac and somatic nociceptive input in rats with STZ-induced diabetes. Type 1 diabetes was induced with streptozotocin (50 mg/kg) in 14 male Sprague–Dawley rats and citrate buffer was injected in 14 control rats. After 4–11...

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Veröffentlicht in:	Autonomic neuroscience 2011-12, Vol.165 (2), p.168-177
Hauptverfasser:	Ghorbani, Marie Louise M, Qin, Chao, Wu, Mingyuan, Farber, Jay P, Sheykhzade, Majid, Fjalland, Bjarne, Nyborg, Niels C.B, Foreman, Robert D
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Angina Animals Autonomic Nervous System - physiopathology Autonomic neuropathy Biological and medical sciences Diabetes Diabetes Mellitus, Experimental - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Extracellular recording Fundamental and applied biological sciences. Psychology Heart - innervation Male Medical Education Medical sciences Neurons, Afferent - physiology Peripheral nervous system. Autonomic nervous system. Neuromuscular transmission. Ganglionic transmission. Electric organ Rats Rats, Sprague-Dawley Spinal Cord - physiopathology Spinal neurons Streptozotocin Thoracic spinal cord Thoracic Vertebrae Vertebrates: nervous system and sense organs
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