Can pharmacogenomics improve malaria drug policy?

Coordinated global efforts to prevent and control malaria have been a tour-de-force for public health, but success appears to have reached a plateau in many parts of the world. While this is a multifaceted problem, policy strategies have largely ignored genetic variations in humans as a factor that...

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Veröffentlicht in:	Bulletin of the World Health Organization 2011-11, Vol.89 (11), p.838-845
Hauptverfasser:	ROEDERER, Mary W, MCLEOD, Howard, JULIANO, Jonathan J
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa Antimalarials - therapeutic use Antiparasitic agents Biological and medical sciences Chemotherapy Cost Costs Decision Making Dosing Drug dosages Drug policy Drug resistance Drug Therapy, Combination Drugs General aspects Genes Genetic diversity Genetic Variation Genetics Genotype & phenotype Global Health Health Policy Health Promotion - methods Health Promotion - standards Human protozoal diseases Humans Infectious diseases Malaria Malaria, Falciparum - drug therapy Malaria, Falciparum - genetics Malaria, Falciparum - prevention & control Medical sciences Medical service Metabolism Metabolites Miscellaneous Parasites Parasitic diseases Pharmacogenetics - methods Pharmacopoeias as Topic - standards Policies Policy & Practice Program Development - methods Protozoal diseases Public Health Public health. Hygiene Public health. Hygiene-occupational medicine Side effects Social Marketing Strategy Success Toxicity Vector-borne diseases
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