MLL gene rearrangements in infant leukemia vary with age at diagnosis and selected demographic factors: A Children's Oncology Group (COG) study

Background Infant leukemias have a high frequency of mixed lineage leukemia (MLL) gene rearrangements. Procedure Using data from a large etiologic study, we evaluated the distribution of selected demographic factors among 374 infant leukemia cases by leukemic subtype, MLL status and diagnosis age. R...

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Veröffentlicht in:	Pediatric blood & cancer 2012-06, Vol.58 (6), p.836-839
Hauptverfasser:	Sam, Thien N., Kersey, John H., Linabery, Amy M., Johnson, Kimberly J., Heerema, Nyla A., Hilden, Joanne M., Davies, Stella M., Reaman, Gregory H., Ross, Julie A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Distribution Age of Onset epidemiology Female Gene Rearrangement Histone-Lysine N-Methyltransferase Humans Infant Infant, Newborn infants Kaplan-Meier Estimate leukemia Leukemia - epidemiology Leukemia - genetics Male MLL Myeloid-Lymphoid Leukemia Protein - genetics Sex Distribution
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