G Protein-coupled Receptors and Resistance to Inhibitors of Cholinesterase-8A (Ric-8A) Both Regulate the Regulator of G Protein Signaling 14 (RGS14)·Gαi1 Complex in Live Cells

Regulator of G protein Signaling 14 (RGS14) is a multifunctional scaffolding protein that integrates both conventional and unconventional G protein signaling pathways. Like other RGS (regulator of G protein signaling) proteins, RGS14 acts as a GTPase accelerating protein to terminate conventional Gα...

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Veröffentlicht in:	The Journal of biological chemistry 2011-11, Vol.286 (44), p.38659-38669
Hauptverfasser:	Vellano, Christopher P., Maher, Ellen M., Hepler, John R., Blumer, Joe B.
Format:	Artikel
Sprache:	eng
Schlagworte:	G protein-coupled Receptors (GPCR) G Proteins GPR Motif Guanine Nucleotide Exchange Factor (GEF) Heterotrimeric G Proteins Receptor Signaling Complex RGS Proteins Signal Transduction
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