Behavioral Pharmacogenetic Analysis on the Role of the α4 GABAA Receptor Subunit in the Ethanol-Mediated Impairment of Hippocampus-Dependent Contextual Learning

Background:  A major effect of low‐dose ethanol is impairment of hippocampus‐dependent cognitive function. α4/δ ‐containing GABAARs are highly expressed within the dentate gyrus region of the hippocampus where they mediate a tonic inhibitory current that is sensitive to the enhancement by low ethano...

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Veröffentlicht in:	Alcoholism, clinical and experimental research clinical and experimental research, 2011-11, Vol.35 (11), p.1948-1959
Hauptverfasser:	Cushman, Jesse D., Moore, Melissa D., Jacobs, Nate S., Olsen, Richard W., Fanselow, Michael S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Behavior Biological and medical sciences Ethanol Hippocampus Learning and Memory Medical sciences Neurosteroid Ro15-4513 Toxicology
Online-Zugang:	Volltext
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