Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates

In invertebrates that harbor functional DNA methylation enzymatic machinery, gene-bodies are the primary targets for CpG methylation. However, virtually all other aspects of invertebrate DNA methylation have remained a mystery until now. Here, using a comparative methylomics approach, we demonstrate...

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Veröffentlicht in:	Genome research 2011-11, Vol.21 (11), p.1841-1850
Hauptverfasser:	Nanty, Lisa, Carbajosa, Guillermo, Heap, Graham A, Ratnieks, Francis, van Heel, David A, Down, Thomas A, Rakyan, Vardhman K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apis mellifera Bombyx mori Ciona intestinalis CpG Islands DNA Methylation Drosophila Drosophila - genetics Drosophila - metabolism Evolution, Molecular Exons Gene Expression Profiling Gene Expression Regulation Genome Histones - metabolism Humans Invertebrata Invertebrates - genetics Invertebrates - metabolism Methylation Nematostella vectensis
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