GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in mice
Tregs not only keep immune responses to autoantigens in check, but also restrain those directed toward pathogens and the commensal microbiota. Control of peripheral immune homeostasis by Tregs relies on their capacity to accumulate at inflamed sites and appropriately adapt to their local environment...
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Veröffentlicht in: | The Journal of clinical investigation 2011-11, Vol.121 (11), p.4503-4515 |
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Sprache: | eng |
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