True single-molecule DNA sequencing of a pleistocene horse bone

Second-generation sequencing platforms have revolutionized the field of ancient DNA, opening access to complete genomes of past individuals and extinct species. However, these platforms are dependent on library construction and amplification steps that may result in sequences that do not reflect the...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Genome research 2011-10, Vol.21 (10), p.1705-1719
Hauptverfasser:	Orlando, Ludovic, Ginolhac, Aurelien, Raghavan, Maanasa, Vilstrup, Julia, Rasmussen, Morten, Magnussen, Kim, Steinmann, Kathleen E, Kapranov, Philipp, Thompson, John F, Zazula, Grant, Froese, Duane, Moltke, Ida, Shapiro, Beth, Hofreiter, Michael, Al-Rasheid, Khaled A S, Gilbert, M Thomas P, Willerslev, Eske
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone and Bones - chemistry Chromosome Mapping DNA - chemistry DNA - isolation & purification DNA Damage DNA Fragmentation Fossils High-Throughput Nucleotide Sequencing - instrumentation High-Throughput Nucleotide Sequencing - methods Horses - genetics Method Sequence Analysis, DNA - instrumentation Sequence Analysis, DNA - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!