Synthetic RNA modules for fine-tuning gene expression levels in yeast by modulating RNase III activity

The design of synthetic gene networks requires an extensive genetic toolbox to control the activities and levels of protein components to achieve desired cellular functions. Recently, a novel class of RNA-based control modules, which act through post-transcriptional processing of transcripts by dire...

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Veröffentlicht in:	Nucleic acids research 2011-10, Vol.39 (19), p.8651-8664
Hauptverfasser:	Babiskin, Andrew H., Smolke, Christina D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Regulation, Fungal Gene Library High-Throughput Screening Assays Regulatory Sequences, Ribonucleic Acid Ribonuclease III - metabolism RNA - chemistry RNA - metabolism Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - metabolism Synthetic Biology and Chemistry
Online-Zugang:	Volltext
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