A double-blind placebo-controlled comparison of a novel formulation of intravenous diclofenac and ketorolac for postoperative third molar extraction pain

Dyloject is a novel formulation of diclofenac intended for intravenous (IV) administration. This formulation employs the solubilizing agent hydroxypropyl-β-cyclodextrin to permit bolus IV administration. The efficacy and safety of 5 dose levels of IV diclofenac were compared with IV ketorolac and pl...

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Veröffentlicht in:	Anesthesia progress 2011-01, Vol.58 (2), p.73-81
Hauptverfasser:	Christensen, Kyle, Daniels, Stephen, Bandy, Donald, Ernst, Cynthia C, Hamilton, Douglas A, Mermelstein, Fred H, Wang, Jianyuan, Carr, Daniel B
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Hydroxypropyl-beta-cyclodextrin Adolescent Adult Aged Analysis of Variance Anti-Inflammatory Agents, Non-Steroidal - administration & dosage beta-Cyclodextrins - administration & dosage Dentistry Diclofenac - administration & dosage Double-Blind Method Drug Combinations Female Humans Injections, Intravenous Kaplan-Meier Estimate Ketorolac - administration & dosage Male Middle Aged Molar, Third - surgery Pain Measurement Pain, Postoperative - prevention & control Scientific Reports Statistics, Nonparametric Tooth Extraction Young Adult
Online-Zugang:	Volltext
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