EDHF: spreading the influence of the endothelium

Our view of the endothelium was transformed around 30 years ago, from one of an inert barrier to that of a key endocrine organ central to cardiovascular function. This dramatic change followed the discoveries that endothelial cells (ECs) elaborate the vasodilators prostacyclin and nitric oxide. The...

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Veröffentlicht in:	British journal of pharmacology 2011-10, Vol.164 (3), p.839-852
Hauptverfasser:	Garland, Christopher J, Hiley, C Robin, Dora, Kim A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioassays Biological Factors - metabolism Blood pressure Blood Pressure - physiology connexins EDHF Endothelium Endothelium, Vascular - metabolism Endothelium, Vascular - physiology Endothelium, Vascular - physiopathology gap‐junctions Humans hyperpolarization KCa2.3 KCa3.1 Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - physiology Muscle, Smooth, Vascular - physiopathology potassium channels Potassium Channels, Calcium-Activated - metabolism prostacyclin Smooth muscle Themed Section: Reviews vasodilatation
Online-Zugang:	Volltext
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