p73-Binding Partners and Their Functional Significance

p73 is one of the tumor-suppressor p53 family of nuclear transcription factor. As expected from the structural similarity between p53 and p73, p73 has a tumor-suppressive function. However, p73 was rarely mutated in human primary tumors. Under normal physiological conditions, p73 is kept at an extre...

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Veröffentlicht in:International Journal of Proteomics 2010-01, Vol.2010, p.13-24
Hauptverfasser: Ozaki, Toshinori, Kubo, Natsumi, Nakagawara, Akira
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Sprache:eng
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