In vivo cancer imaging by poly(ethylene glycol)- b -poly(ɛ-caprolactone) micelles containing a near-infrared probe

Abstract Noninvasive near-infrared (NIR) fluorescence imaging is a promising technique for the intraoperative assessment of solid tumor removal. We incorporated a lipophilic NIR probe, 1,1′-dioctadecyltetramethyl indotricarbocyanine iodide (DiR), in poly(ethylene glycol)- b -poly(ɛ-caprolactone) (PE...

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Veröffentlicht in:	Nanomedicine 2012-02, Vol.8 (2), p.228-236
Hauptverfasser:	Cho, Hyunah, MS, Indig, Guilherme L., PhD, Weichert, Jamey, PhD, Shin, Ho-Chul, MS, Kwon, Glen S., PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbocyanines - chemistry Diagnostic Imaging - methods Fluorescent Dyes - chemistry Humans Internal Medicine Micelles Near infrared (NIR) fluorescence imaging Neoplasms - diagnosis Particle Size Poly(ethylene glycol)- b-poly(ɛ-caprolactone) Polyesters - chemistry Polyethylene Glycols - chemistry Polymeric micelles Self-quenching Solubility Water
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