FABP7 expression in normal and stab-injured brain cortex and its role in astrocyte proliferation

Reactive gliosis, in which astrocytes as well as other types of glial cells undergo massive proliferation, is a common hallmark of all brain pathologies. Brain-type fatty acid-binding protein (FABP7) is abundantly expressed in neural stem cells and astrocytes of developing brain, suggesting its role...

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Veröffentlicht in:	Histochemistry and cell biology 2011-11, Vol.136 (5), p.501-513
Hauptverfasser:	Sharifi, Kazem, Morihiro, Yusuke, Maekawa, Motoko, Yasumoto, Yuki, Hoshi, Hisae, Adachi, Yasuhiro, Sawada, Tomoo, Tokuda, Nobuko, Kondo, Hisatake, Yoshikawa, Takeo, Suzuki, Michiyasu, Owada, Yuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Antigens - metabolism Astrocytes Astrocytes - metabolism Astrocytes - pathology Biochemistry Biomedical and Life Sciences Biomedicine Brain Brain damage Cell Biology Cell Proliferation Cells, Cultured Cellular biology Cerebral Cortex - injuries Cerebral Cortex - metabolism Cortex Data processing Developmental Biology Differentiation Disease Models, Animal Fatty acid-binding protein Fatty Acid-Binding Protein 7 Fatty Acid-Binding Proteins - genetics Fatty Acid-Binding Proteins - metabolism Fatty acids Fatty Acids, Omega-3 - metabolism Gene Expression Glial cells Glial fibrillary acidic protein Glial stem cells Gliosis Gliosis - metabolism Gliosis - pathology Homeostasis Immunohistochemistry Injuries Lipid metabolism Male Mice Mice, Inbred C57BL Mice, Knockout Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Neural stem cells Neural Stem Cells - metabolism Neural Stem Cells - pathology Oligodendroglia - metabolism Oligodendroglia - pathology Original Paper Proteoglycans - metabolism Western blotting Wounds, Stab - genetics Wounds, Stab - metabolism Wounds, Stab - pathology
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